A gumma is a soft, tumor-like growth of the tissues (granuloma) that occurs in people with syphilis.
A gumma is caused by the bacteria that causes syphilis. It appears during late-stage tertiary syphilis. It usually contains a mass of dead and swollen fiber-like tissue, and occurs most often in the liver. It also can occur in the:
Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Bellevue, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.